CALCIUM CARBONATE ANTACIDs

Tablet(chewable)
Calcium carbonate antacid preparation is
available as calcium carbonate BP 1000mg
chewable tablet.

Mode of action: Calcium carbonate antacid
works by simple acid-base neutralization
reaction. Thus, it consumes the excess stomach
acid & relieves the hyperacidity related
symptoms.

ALUMlNIUM + MAGNESIUM ANTACIDs

Tablet/Suspension
Aluminum & magnesium antacid preparations are non-systemic antacids. These are not significantly absorbed from the gut and mainly used as antacids such as, aluminum hydroxide, magnesium hydroxide, magnesium trisilieate.

Antacids

Definition: Antacids are the most useful drugs for relief of hyperacidity & associated pain.
Antacid preparations are weakly basic and consist of metal salts, most cOD1Jl1only alluminium
hydroxide, magnesium hydroxide,calcium carbonate or sodium bicarbonate.

Classification: Antacids are classified as:
i. Systemic antacids:
Which are usually absorbed from the gut so, these are preferable as blood
alkaliser to combat acidosis rather than antacids,such as sodium bicarbonate, sodium citrate, sodium acetate, potassium citrate.

ii. Non-systemic antacids:
These are not significantly absorbed from the gut and mainly used as antacids such as; aluminium hydroxide, magnesium hydroxide, magnesiul11 trisilicate.

DRUGS ACTING ON THE ALIMENTARY SYSTEM

The drugs and preparations acting on the
alimentary system are classified into the
following broad groups:
1. Antacids & other anti-dyspeptic drugs.
2. Antispasmodics (anticholinergics).
3. Anticholinergic & anti-psychotic
combination products.
4. Motility stimulants/Dopamine antagonists.
5. Ulcer-healing drugs.
6. Antidiarrhoeal drugs.
7. Drugs in chronic inflammatory bowel
diseases.
8. Preparations for aphthous ulcer.
9. Laxatives, purgatives & lubricants.
10. Local preparations for anal and rectal
disorders.
11. Drugs affecting intestinal secretions.